SPYRE THERAPEUTICS INC
8 of the Top-200 alpha managers hold $SYRE as of the latest 13F snapshot.
Smart Money · top-200 alpha cohort
8 holders · Q1 2026$SYRE is held by 8 managers from the Top-Performer cohort as of Q1 2026. Position weights range from 0.00% to 1.62%, with an average of 0.34% of portfolio. Largest holder: Fidelis Capital Partners, LLC at 1.62%. A weekly Smart-Money commentary for this ticker has not been generated yet this batch — the table below shows the full cohort positioning.
Smart Money shows holdings from our Top-Performer cohort — the 200 highest-alpha manager_13f funds in our universe. Position weight (current quarter) and QoQ delta versus prior quarter. α is the manager's annual alpha vs benchmark.
Institutional holders
Top 10 of 191 · Source: 13F-HRInsider activity · last 90 days
13 transactions · 3 filersTransaction codes: P open-market purchase · S sale · M option exercise · A grant · F tax-withhold sale. Insider names link to each individual's expert page.
Congress trades · last 90 days
No STOCK Act filings reference $SYRE in the recent window.
Source data: SEC EDGAR · 13F-HR · Form 4 · U.S. House Clerk PTR (disclosures-clerk.house.gov) · Senate eFD (senate.gov) · Last refreshed 07:07 UTC.