SPERO THERAPEUTICS ORD

$SPRO
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Institutional coverage

50 13F filers hold $SPRO.

13F holders
50
Insider buys · 90d
0
Congress · 90d
0

Smart Money · top-200 alpha cohort

2 holders · Q1 2026

Fewer than 3 top-performer holders hold this ticker — not enough signal for a Smart-Money commentary this week. The institutional holders table below shows the full picture.

01
Ionic Capital Management LLC
0.04% held
α +17.9pts
02
Citigroup Inc.
0.00% held
α +26.3pts

Smart Money shows holdings from our Top-Performer cohort — the 200 highest-alpha manager_13f funds in our universe. Position weight (current quarter) and QoQ delta versus prior quarter. α is the manager's annual alpha vs benchmark.

Institutional holders

Top 10 of 50 · Source: 13F-HR
01
GSK plc
2.68% of portfolio
9,190,606 sh
02
Jennison Associates LLC
2.31% of portfolio
2,362,348 sh
03
Eads & Heald Wealth Management
—
1,189,235 sh
04
Empire Life Investments Inc.
0.05% of portfolio
889,979 sh
05
Leuthold Group, LLC
—
885,631 sh
06
Evercore Wealth Management, LLC
0.09% of portfolio
421,956 sh
07
Minneapolis Portfolio Management Group, LLC
—
300,724 sh
08
Benin Management CORP
0.04% of portfolio
278,304 sh
09
Mesirow Financial Investment Management, Inc.
—
216,600 sh
10
Axa S.a.
—
214,751 sh
See all 50 13F holders · Pro →

Insider activity · last 90 days

1 transactions · 1 filers
04 May 2026
Rajavelu Esther —
▼ SOLD
25,240
$2.51
S

Transaction codes: P open-market purchase · S sale · M option exercise · A grant · F tax-withhold sale. Insider names link to each individual's expert page.

Congress trades · last 90 days

No Congress trades

No STOCK Act filings reference $SPRO in the recent window.

Source data: SEC EDGAR · 13F-HR · Form 4 · U.S. House Clerk PTR (disclosures-clerk.house.gov) · Senate eFD (senate.gov) · Last refreshed 10:02 UTC.